MUNICH UNIVERSITY ASTHMA AND ALLERGY RESEARCH GROUP

Erika von Mutius is head of the Asthma and Allergy Department of Munich University Children’s Hospital in Munich, Germany. Professor von Mutius completed her internship and residency training in the Department of General Pediatrics, Neonatal and Pediatric Intensive Care at this hospital. From 1992-1993 she was a research fellow at the Respiratory Sciences Center at the University of Arizona, Tucson, USA, with Professor Fernando Martinez, and also received training in Clinical Effectiveness at Harvard School of Public Health in Boston, USA. In 2004 she was appointed as Professor of Pediatrics at Ludwig-Maximilians-Universität, Munich, one of only nine Centres of Excellence in Germany.

Her research interests have been focused on the epidemiology of paediatric respiratory and allergic diseases for many years. She has worked in several multicentre and interdisciplinary projects addressing the potential role of genetic and environmental determinants of atopic illnesses and has a 20 year experience with design, implementation and data analysis of large multicentre epidemiological studies on paediatric respiratory diseases and allergies, including birth cohort studies.

Professor von Mutius has been the recipient of several prestigious awards. She serves on a number of international committees and is an active editorial board member of national and international journals such as the New England Journal of Medicine.

Publications
Papers in peer reviewed journals:
1. von Mutius E, Nicolai T, Lehmacher W, Reitmeir P, Stiepel E. Gibt es Risikofaktoren der stenosierenden Laryngitis? Monatschr Kinderheilk, 1989;137:716-21.
2. von Mutius E, Nicolai T, Stiepel E, Frentzel-Beyme R, Reitmeir P, Wulff A, Lehmacher W, von Loeffelholz E, Berbig B, Adam D. Prävalenz von kindlichem Asthma bronchiale und Allergien in München. Münch Med Wschr 1989;131:850-2.
3. Berbig B, von Mutius E, Nicolai T, Stiepel E, Adam D. Untersuchungen zu einem multiallergenen Teststempel im Vergleich zum Prick-Test. Allergologie 1991;2:51-7.
4. Wjst M, Dold S, Reitmeir P, Wulff A, Nicolai T, von Mutius E. Schützt Stillen vor Asthma und Allergien ? Ergebnisse der Münchner Asthma- und Allergiestudie. Monatschr Kinderheilk 1992;140:769-74.
5. Dold S, Reitmeir P, Wjst M, von Mutius E. Auswirkungen des Passivrauchens auf den kindlichen Respirationstrakt. Monatschr Kinderhlk 1992;140:763-8.
6. Dold S, Wjst M, von Mutius E, Reitmeir P, Stiepel E. Genetic risk for asthma, allergic rhinitis, and atopic dermatitis. Arch Dis Child 1992;67:1018-22.
7. Wjst M, Dold S, Reitmeir P, Stiepel E, von Mutius E. Month of birth and allergic disease at the age of 10. Clin Exp Allergy 1992;22:1026-31.
8. von Mutius E, Fritzsch Ch, Weiland SK, Roell G, Magnussen H. Prevalence of asthma and allergic disorders among children in united Germany: a descriptive comparison. Br Med J 1992:305;1395-1399.
9. Weiland SK, Kugler J, von Mutius E, Schmitz N, Fritzsch C, Wahn U, Keil U. Die Sprache asthma-kranker Kinder: eine Untersuchung zur Symptombeschreibung. Monatschr Kinderheilk 1993;141:878-82.
10. Nicolai T, von Mutius E, Reitmeir P, Wjst M. Reactivity to cold air hyperventilation in normal and asthmatic children in a survey of 5697 school children in Southern Bavaria. Am Rev Resp Dis 1993;147:565-72.
11. von Mutius E, Nicolai T, Martinez FD. Prematurity as a risk factor for asthma in preadolescent children. J Ped 1993;123:223-29.
12. Wjst M, Reitmeir P, Dold S, Wulff A, Nicolai T, von Loeffelholz-Colberg E, von Mutius E. Road traffic and adverse effects on respiratory health in children. Br Med J 1993;307:596-600.
13. Wjst M, Dold S, Reitmeir P, Wulff A, Nicolai T, von Mutius E. Evaluation of cold air challenge data in a population sample using a model of bronchial hyperreactivity and disposition to bronchial obstruction. Ped Pulmonol 1993; 15:339-44.
14. Fritzsch C, von Mutius E, Weiland SK, Röll G, Magnussen H. Prävalenz asthmatischer und allergischer Erkrankungen bei Schulkindern - ein Vergleich zwischen Leipzig und München. Allergo J 1994;3:11-6.
15. von Mutius E, Martinez FD, Fritzsch C, Nicolai T, Reitmeir P, Thiemann HH. Skin test reactivity and number of siblings. Br med J 1994;308:692-5.
16. von Mutius E, Martinez FD, Fritzsch C, Nicolai T, Reitmeir P, Thiemann HH. Prevalence of asthma and atopy in two areas of West and East Germany. Am J Resp Crit Care Med 1994; 149:358-64.
17. Schulz A, Tuch T, Brand P, Schulz H, Erdl R, von Mutius E, Reinhardt D, Heyder J. Aerosol bolus dispersion in the respiratory tract of children. Exp Lung Res 1994;20:119-30.
18. Wjst M, Dold S, Reitmeir P, Fritzsch C, von Mutius E, Thiemann HH. Pertussis infection and allergic sensitization. Ann Allergy 1994;73:450-4.
19. Wjst M, Dold S, Roell G, Reitmeir P, Fritzsch C, von Mutius E, Thiemann HH. Bronchial hyperreactivity and history of wheezing in children. Eur J Pediatr 1994;153:682-6.
20. von Mutius E, Sherrill DL, Fritzsch Ch, Martinez FD, Lebowitz MD. Air pollution and upper respiratory symptoms in children from East Germany. Eur Resp J 1995;8:723-8.
21. Schulz H, Schulz A, Brand P, Tuch T, von Mutius E, Erdl R, Reinhardt D, Heyder J. Aerosol bolus dispersion and effective airway diameters in mildly asthmatic children. Eur Resp J 1995;8:566-73.
22. von Mutius E, Nicolai T. Familial aggregation of asthma in a South Bavarian population. Am J Respir Crit Care Med 1996;153:1266-72.
23. von Mutius E, Illi S, Nicolai T, Martinez FD. Relation of indoor heating with asthma, allergic sensitization, and bronchial responsiveness in South Bavarian children. Br Med J 1996; 312:1448-50.
24. Rosenecker J, Harms HK, Bertele RM, Pohl-Kopppe A, von Mutius E, Adam D, Nicolai T. Adenovirus infection in cystic fibrosis patients: implications for the use of adenoviral vectors for gene transfer. Infection 1996;24:5-8.
25. Nicolai T, v Mutius E. Risk of asthma in children with a history of croup. Acta Paediatrica 1996;85:1295-9.
26. Nicolai T, Bellach B, von Mutius E, Thefeld W, Hoffmeister H. Increased prevalence of sensitization against aeroallergens in adults in West- compared to East-Germany. Clin Exp Allergy 1997;27:886-92.
27. Buss M, von Mutius E, Müller KM, Nicolai Th, Döhlemann C. Pulmonale Hypertonie als letale Komplikation einer exogen allergischen Alveolitis. Monatsschr Kinderheilkd 1997;145:901-5.
28. Illi S, Garcia-Marcos L, Hernando V, Guillen JJ, Liese A, von Mutius E. Reproducibility of skin prick test results in epidemiological studies: a comparison of two devices. Allergy 1998;53:353-8.
29. Strachan D, Sibbald B, Weiland S, Ait-Khaled N, Anabwani G, Anderson HR, Asher MI, Beasley R, Björksten B, Burr M, Clayton T, Crane J, Ellwood P, Keil U, Lai C, Mallol J, Martinez F, Mitchell E, Montefort S, Pearce N, Robertson C, Shah J, Stewart A, von Mutius E, Williams H. Worlwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children: the International Study of Asthma and Allergies in Childhood (ISAAC). Ped Allerg Immunol 1997; 8: 161-76.
30. ISAAC Steering Committee (Writing Committee: Asher MI, Anderson HR, Stewart AW, Crane J). Worldwide variations in the prevalence of asthma symptoms: the International Study of Asthma and Allergies in Childhood (ISAAC). Eur Resp J 1998;12:315-35.
31. ISAAC Steering Committee (Writing Committee: Beasley R, Keil U, von Mutius E, Pearce N). Worldwide variations in the prevalence of atopic diseases: the International Study of Asthma and Allergies in Childhood (ISAAC). Lancet 1998; 351: 1225-32.
32. Williams, H., C. Robertson, A. Stewart, N. Ait-Khaled, G. Anabwani, R. Anderson, I. Asher, R. Beasley, B. Bjorksten, M. Burr, T. Clayton, J. Crane, P. Ellwood, U. Keil, C. Lai, J. Mallol, F. Martinez, E. Mitchell, S. Montefort, N. Pearce, J. Shah, B. Sibbald, D. Strachan, E. von Mutius, and S. Weiland. Worldwide variations in the prevalence of symptoms of atopic eczema in the International Study of Asthma and Allergies in Childhood. J Allergy Clin Immunol 1998;103:125-38.
33. von Mutius E, Weiland SK, Fritzsch C, Duhme H, Keil U. Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany. Lancet 1998;351:862-6.
34. von Mutius E, Weiland SK, Fritzsch C, Duhme H, Keil U. Increase of allergy in East Germany - reply. Lancet 1998;351:1814.
35. von Mutius E, Weiland SK, Fritzsch C, Duhme H, Keil U. Prevalence of hay fever and consumption of margarine in East Germany - reply. Lancet 1998;352:318.
36. Nicolai T, Illi S, von Mutius E. Dampness at home in childhood is a risk factor for bronchial hyperreactivity in adolescence. Thorax 1998;53:1035-40.
37. Kabesch M, Schaal W, Nicolai T, von Mutius E . Lower prevalence of asthma and atopy in Turkish children living in Germany. Eur Resp J 1999;13:577-82.
38. Kabesch M, Schaal W, Nicolai T, von Mutius E. Asthma bronchiale bei türkischen und deutschen Schulkindern: Häufigkeit, Schweregrad und Behandlung. Monatschr Kinderh 1999;147:328-32.
39. Weiland SK, von Mutius E, Hüsing A, Asher MI. Intake of trans fatty acids and prevalence of childhood asthma and allergies in Europe. Lancet 1999;353:2040-1.
40. von Mutius E, Illi S, Hirsch T, Leupold W, Keil U, Weiland S. Frequency of infections in the first years of life and risk of asthma, atopy and airway hyperresponsiveness among schoolage children. Eur Resp J 1999;14:4-11.
41. von Ehrenstein O, von Mutius E, Illi S, Baumann L, Böhm O, von Kries R. Reduced risk of hay fever and asthma among children of farmers. Clin Exp Allergy 2000; 30:187-93.
42. von Kries R, Hermann M, Grunert VP, von Mutius E. Is obesity a risk factor for childhood asthma ? Allergy 2001;56:318-22.
43. Niggemann B, Illi S, Madloch C, Völkel K, Lau S, Bergmann R, von Mutius E, Wahn U and the MAS-Study Group. Bronchial histamine challenges in 7 year old children: a PC20FEV1 below 1.0 mg/ml discriminates between symptomatic and non-symptomatic children. Eur Resp J 2001;17:246-53.
44. Liese AD, Weiland SK, Hirsch T, von Mutius E, Leupold W, Keil U. Inverse association of overweight and breast feeding in 9-10 year old children in Germany. Int J Obes Relat Metab Disord. 2001 Nov;25(11):1644-50.
45. Niggemann B, Illi S, Madloch C, Volkel K, Lau S, Bergmann R, von Mutius E, Wahn U; MAS-Study Group. Multicentre Allergy Study. Histamine Challenges discriminate between symptomatic and asymptomatic children. MAS-Study Group. Multicentre Allergy Study. Eur Respir J. 2001;17:246-53.
46. Renz H, von Mutius E, Illi S, Wolkers F, Hirsch T, Weiland SK. TH-1 / TH-2 immune response profiles differ between atopic children in East and West Germany. J Allergy Clin Immunol 2002;320:338-42.
47. von Ehrenstein OS, von Mutius E, Maier E, Hirsch T, Schaal W, Carr D, Roscher AA, Olgemöller B, Nicolai T, Weiland SK. Lung function of school children with low levels of Alpha1-Antitrypsin and tobacco smoke exposure. Eur Respir J.2002;19:1099-106.
48. Illi S, von Mutius E, Lau S, Bergmann R, Niggemann B, Sommerfeld C, Wahn U and the MAS Study Group. Early childhood infectious diseases and the development of asthma up to school age: a birth cohort study. Br Med J 2001;322:390-5.
49. Ellwood P, Asher MI, Björksten B, Burr M, Pearce N, Robertson CF and the ISAAC Phase One Study Group. Diet and asthma, allergic rhinoconjunctivitis and atopic eczema symptom prevalence: an ecological analysis of the International Study of Asthma and Allergies in Childhood (ISAAC) data. Eur Respir J 2001;17:436-43.
50. Nicolai T, Illi S, Tenbörg J, Kiess W, von Mutius E. Puberty and prognosis of asthma and bronchial hyperreactivity. Pediatr Allergy Immunol 2001;12:142-48.
51. Wahn U, von Mutius E. Childhood risk factors for atopy and the importance of early intervention. J Allergy Clin Immunol. 2001;107:567-74.
52. von Mutius E, Schwartz K, Neas LM, Dockery D, Weiss ST. Relation of body mass index to asthma and atopy in children: the National health and Nutrition Examination Study III. Thorax 2001;56:0-3.
53. Beimfohr C, Maziak W, von Mutius E, Hense HW. Leupold W, Hirsch T, Keil U, Weiland SK. The use of anti-asthmatic drugs in children: results of a community-based survey in Germany. J Pharmacoepidemiol and drug safety 2001;10:315-21.
54. Riedler J, Braun-Fahrländer C, Eder W, Schreuer M, Waser M , Maisch S, Carr D, Schierl R, Nowak D, von Mutius E and the ALEX Study Team. Early life exposure to farming provides protection against the development of asthma and allergy. Lancet 2001;358:1129-33.
55. von Mutius E. Infection: friend or foe in the development of atopy and asthma ? The epidemiological evidence. Eur Respir J 2001;18:872-881.
56. Kusser B, Braun A, Praun M, Illi S, von Mutius E, Roscher AA. Polymorphisms of the bradykinin B2 receptor gene and childhood asthma. Biol Chem 2001;382:885-9.
57. Illi S, von Mutius E, Lau S, Nickel R, Niggemann B, Sommerfeld C, Wahn U and the MAS Study Group. The pattern of atopic sensitization is associated with the development of asthma in childhood. J Allergy Clin Immunol 2001;108:709-14.
58 . Maziak W, von Mutius E, Beimfohr C, Hirsch T, Leupold W, Keil U, Weiland SK. The management of childhood asthma in the community. Eur Respir J 2002;20:1476-82 .
59. Carr D, von Ehrenstein O, Weiland S, Wagner C, Wellie O, Nicolai T, von Mutius E. Modeling annual benzene, toluene, NO2, and soot concentrations on the basis of road traffic characteristics. Environ Res 2002;90:111-8.
60. Braun-Fahrländer C, Riedler J, Herz U, Eder W, Waser M, Grize L, Maisch S, Carr D, Gerlach F, Bufe A, Lauener RP, Schierl R, Renz H, Nowak D, von Mutius E; Allergy and Endotoxin Study Team. Environmental exposure to endotoxin and its relation to asthma in school-age children. N Engl J Med 2002;347:869-77.
61. Lauener RP, Birchler T, Adamski J, Braun-Fahrländer C, Bufe A, Herz U, von Mutius E, Nowak D, Riedler J, Waser M, Sennhauser FH; ALEX study group. Expression of CD14 and Toll-like receptor 2 in farmers’ and non-farmers’ children. Lancet 2002;360:465-6
62. Kabesch M, Peters W, Carr D, Leupold W, Weiland SK, von Mutius E. Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations. J Allergy Clin Immunol 2003;111:813-7.
63. Nicolai T, Carr D, Weiland SK, Duhme H, von Ehrenstein O, Wagner C, von Mutius E. Urban traffic and pollutant exposure related to respiratory outcomes and atopy in a large sample of children. Eur Respir J 2003;21:956-63.
64. Nicolai T, Pereszlenyiova-Bliznakova L, Illi S, Reinhardt D, von Mutius E. Longitudinal follow-up of the changing gender ratio in asthma from childhood to adulthood : role of delayed manifestation in girls. Pediatr Allergy Immunol 2003;14:280-3.
65. Oberle D, von Mutius E, von Kries R. Childhood asthma and continuous exposure to cats since the first year of life with cats allowed in the child’s bedroom. Allergy 2003; 58:1033-6.
66. Allen M, Heinzmann A, Noguchi E, Abecasis G, Broxholme J, Ponting CP, Bhattacharyya S, Tinsley J, Zhang Y, Holt R, Jones EY, Lench N, Carey A, Jones H, Dickens NJ, Dimon C, Nicholls R, Baker C, Xue L, Townsend E, Kabesch M, Weiland SK, Carr D, von Mutius E, Adcock IM, Barnes PJ, Lathrop GM, Edwards M, Moffatt MF, Cookson WO. Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat Genet 2003;35:258-63.
67. Kabesch M, Tzotcheva I, Carr D, Hofler C, Weiland SK, Fritzsch C, von Mutius E, Martinez FD. A complete screening of the IL4 gene: novel polymorphisms and their association with asthma and IgE in childhood. J Allergy Clin Immunol 2003;112:893-8.
68. von Ehrenstein OS, Maier EM, Weiland SK, Carr D, Hirsch T, Nicolai T, Roscher AA, von Mutius E. Alpha1 antitrypsin and the prevalence and severity of asthma. Arch Dis Child 2004;89:230-1.
69. Eder W, Klimecki W, Yu L, von Mutius E, Riedler J, Braun-Fahrländer C, Nowak D, Martinez FD; ALEX Study Team. Toll-like receptor 2 as a major gene for asthma in children of European farmers. J Allergy Clin Immunol 2004;113:482-8.
70. Foliaki S, Nielsen SK, Bjorksten B, von Mutius E, Cheng S, Pearce N. Antibiotic sales and the prevalence of symptoms of asthma, rhinitis, and eczema: The International Study of Asthma and Allergies in Childhood (ISAAC). Int J Epidemiol 2004;33:558-63.
71. Bolte G, Schmidt M, Maziak W,. Keil U, Nasca P, von Mutius E, Weiland SK. The relation of markers of fetal growth with asthma, allergies and serum immunoglobulin E levels in children at age 5-7 years. Clin Exp Allergy 2004;34:381-8.
72. Waser M, Schierl R, von Mutius E, Maisch S, Carr D, Riedler J, Eder W, Schreuer M, Nowak D, Braun-Fahrländer C; ALEX Study Team. Determinants of endotoxin levels in living environments of farmer’s children and their peers from rural areas. Clin Exp Allergy 2004;34:389-97.
73. Zutavern A, von Mutius E, Harris J, Mills P, Moffatt S, White C, Cullinan P. The introduction of solids in relation of asthma and eczema. Arch Dis Child 2004;89:303-8.
74. Kabesch M, Hoefler C, Carr D, Leupold W, Weiland SK, von Mutius E. Glutathione S transferase deficiency and passive smoking increase childhood asthma. Thorax 2004;59:569-73.
75. Holt PG, Sly PD Martinez FD, Weiss ST, Bjorsten B, von Mutius E, Wahn U. Drug development strategies for asthma: in search of a new paradigm. Nat Immunol 2004;5:695-8.
76. Maziak W, von Mutius E, Keil U, Hirsch T, Leupold W, Rzehak P. Behrens T, Weiland SK. Predictors of health care utilization in children with asthma in the community. Pediatr Allergy Immunol 2004;15:166-71.
77. Kabesch M, Carr D, Weiland SK, von Mutius E. Association between polymorphisms in serine protease inhibitor, kazal type 5 and asthma phenotypes in a large German population sample. Clin Exp Allergy 2004;34:340-5.
78. Wong GWK, Ko FWS, Hui DSC, Fok TF, Carr D, von Mutius E, Zhong NS, Chen YZ, Lai CKW. Factors associated with difference in prevalence of asthma in children from three cities in China: multicentre epidemiological survey. Brit Med J 2003;329:486-90.
79. Radon K, Windstetter D, Eckart J, Dressel H, Leitritz L, Reichert J, Schmid M, Praml G, Schosser M, von Mutius E, Nowak D. Farming exposure in childhood, exposure to markers of infections and the development of atopy in rural subjects. Clin Exp Allergy 2004;34:1178-1183.
80. van Strien RT, Engel R, Holst O, Bufe A, Eder W, Waser M, Braun-Fahrländer C, Riedler J, Nowak D, von Mutius E; ALEX Study Team. Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health. J Allergy Clin Immunol 2004;113:860-7.
81. Weiland SK, Bjorksten B, Brunekreef B, Cookson WO, von Mutius E, Strachan DP. Phase II of the International Study of Asthma and Allergies in Childhood (ISAAC II) rationale and methods. Eur Respir J 2004;24:406-12.
82. Illi S, von Mutius E, Lau S, Nickel R, Gruber C, Niggemann B, Wahn U; Multicenter Allergy Study Group. The natural course of atopic dermatitis from birth to age 7 years and the association with asthma. J Allergy Clin Immunol 2004;113:925-31.
83. Radon K, Windstetter D, Eckart J, Dressel H, Leitritz L, Reichert J, Schmid M, Praml G, von Mutius E, Nowak D. Kontakt zu landwirtschaftlichen Betrieben und Toxoplasma-gondii-Infektionen. Allergo Journal 2004;13:524-527.
84. Schedel M, Carr D, Klopp N, Woitsch B, Illig T, Stachel D, Schmid I, Fritzsch C, Weiland SK, von Mutius E, Kabesch M. A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels. J Allergy Clin Immunol. 2004;114:1100-5.
85. Waser M, von Mutius E, Riedler J, Nowak D, Maisch S, Carr D, Eder W, Teboew G, Schierl R, Schreuer M, Braun-Fahrländer C and the ALEX Study team. Exposure to pets, and the association with hay fever, asthma, and atopic sensitization in rural children. Allergy 2005;60:177-84.
86. Liese AD, Hirsch Th, von Mutius E, Weiland SK. Prevalence and dietary correlates of overweight and obesity in former East and West German children. Eur J Public Health. 2006 Oct;16(5):526-31.
87. Kormann MSD, Carr D, Klopp N, Illig T, Leupold W, Fritzsch C, Weiland SK, von Mutius E, Kabesch M. G-Protein coupled receptor polymorphisms are associated with asthma in a large German population. Am J Respir Crit Care Med 2005;171:1358-62.
88. Üblagger E, Schreuer M, Eder W, von Mutius E, Benz M.R., Braun-Fahrländer C, Moeller A, Brunekreef B, Schram D, Wickman M, Swartz J and Pershagen G, Riedler J on behalf of the PARSIFAL study group. Validation of questions on asthma and wheeze in farming and anthroposophic children. Clin Exp Allergy 2005; 35:1033–1039.
89. Melén E, Bruce S, Doekes G, Kabesch M, Laitinen T, Lauener R, Lindgren C, Riedler J, Scheynius A, van Hage-Hamsten M, Kere J, Pershagen G, Wickman M, Nyberg F, and the PARSIFAL Genetics study group. G-protein-coupled receptor for asthma susceptibility (GPRA) haplotypes are associated with childhood allergy and asthma - the PARSIFAL and BAMSE studies. Am J Respir Crit Care Med 2005;171:1089-95.
90. Eder W, Klimecki W, Yu L, von Mutius E, Riedler J, Braun-Fahrländer C, Nowak D, Martinez FD and the ALEX Study Team. Opposite effects of CD14/-260 on serum IgE levels in children raised in different environments. J Allergy Clin Immunol 2005; 116:601-7.
91. Zöllner IK, Weiland SK, Piechotowski I, Gabrio T, von Mutius E, Link B, Pfaff G, Kouros B, Wuthe J. No increase in the prevalence of asthma, allergies, and atopic sensitisation among children in Germany: 1992-2001. Thorax 2005;60:545-548.
92. Radon K, Windstetter D, Solfrank S, von Mutius E, Nowak D, Schwarz HP and the CAT study group. Exposure to farming environments in early life and type 1 diabetes mellitus: A case-control study. Diabetes 2005;54:3212–3216.
93. Schram-Bijkerk D, Doekes G, Douwes J, Boeve M, Riedler J, Üblagger E, von Mutius E, Benz MR, Pershagen G, van Hage M, Scheynius A, Braun-Fahrländer C, Waser M, Brunekreef B, on behalf of the PARSIFAL study group. Bacterial and fungal agents in house dust and wheeze in children - the PARSIFAL study. Clin Exp Allergy 2005;35:1272-8.
94. Zutavern A, Hirsch T, Leupold W, Weiland S, Keil U, von Mutius E. Atopic dermatitis, extrinsic atopic dermatitis and the hygiene hypothesis: Results from a cross-sectional study. Clin Exp Allergy, 2005; 35:1301–1308.
95. Flöistrup H, Swartz J, Bergström A, Alm JS, Scheynius A, van Hage M, Waser M, Braun-Fahrländer C, Schram-Bijkerk D, Huber M, Zutavern A, von Mutius E, Üblagger E, Riedler J, Michels KB, Pershagen G, and the PARSIFAL study group. Allergic disease and sensitisation in Steiner school children. J Allergy Clin Immunol 2006;117: 59-66.
96. Bolte G, Kompauer I, Fobker M, Cullen P, Keil U, von Mutius E, Weiland SK. Fatty acids in serum cholesteryl esters in relation to asthma and lung function in children. Clin Exp Allergy 2006; 36:293–302.
97. Peters M, Kauth M, Schwarze J, Körner-Rettberg C, Riedler J, Nowak D, Braun-Fahrländer C, von Mutius E, Bufe A, Holst O and the ALEX Study Group. Inhalation of stable dust extract prevents allergen induced airway inflammation and hyper-responsiveness. Thorax 2006;61:134-9.
98. Schedel M, DepnerM, Schoen C, Weiland S, Vogelberg C, Niggemann B, Lau S, Fritzsch C, Illig T, Klopp N, Wahn U, von Mutius E, Nickel R, Kabesch M. The role of ADAM33, A disintegrin and metalloprotease 33, in Asthma and BHR in two German populations. Respir Res. 2006 Jun 19;7:91.
99. Schram-Bijkerk D; Doekes G; Boeve M; Douwes J; Riedler J; Üblagger E; von Mutius E; Benz M; Pershagen G; Wickman M; Alfvén T; Braun-Fahrländer C; Waser M; Brunekreef B on behalf of the PARSIFAL study group. Exposure to microbial components and allergens in population studies: A comparison of two house dust collection methods applied by participants and fieldworkers. Indoor Air 2006 Dec;16: 414-25.
100. Radon K, Riu E, Dressel H, Windstetter D, Weinmayr G, Weiland S, Vogelberg C, Scharrer EM, Leupold W, von Mutius E, Nowak D. Adolescents’ jobs and the course of dermatitis symptoms throughout puberty. Scand J Work Environ Health 2006; 32:132-7.
101. Radon K, Huemmer S, Dressel H, Windstetter D, Weinmayr G, Weiland S, Riu E, Vogelberg C, Leupold W, von Mutius E, Goldberg M, Nowak D. Do respiratory symptoms predict job choices in teenagers? Eur Respir J 2006; 27: 774–778.
102. Kabesch M, Schedel M, Carr D, Woitsch B, Fritzsch C, Weiland SK, von Mutius E. IL-4/IL-13 pathway genetics strongly influence serum IgE levels and childhood asthma. J Allergy Clin Immunol. 2006;117:69-74.
103. Ege MJ, Bieli C, Frei R, van Strien RT, Riedler J, Üblagger E, Schram-Bijkerk D, Brunekreef B, van Hage M, Scheynius A, Pershagen G, Benz MR, Lauener R, von Mutius E, Braun-Fahrländer C and the PARSIFAL Study team. Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children. J Allergy Clin Immunol. 2006;117:817-23.
104. Liese AD, Hirsch T, von Mutius E, Weiland SK. Burden of overweight in Germany: prevalence differences between former East and West German children. Eur J Public Health. 2006 Oct;16(5):526-31.
105. Asher MI, Montefort S, Björkstén B, Lai CKW, Strachan DP, Weiland SK, Williams H and the ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis and eczema in childhood - ISAAC Phase Three. Lancet. 2006 Aug 26;368(9537):733-43.
106. Illi S, von Mutius E, Lau S, Niggemann B, Grüber C, Wahn U and on behalf of the Multicentre Allergy Study (MAS) group. Perennial allergen sensitisation early in life and chronic asthma in children: a birth cohort study. Lancet 2006; 368: 763-770.
107. Genuneit J, Weinmayr G, Radon K, Dressel H, Windstetter D, Rzehak P, Vogelberg C, Leupold W, Nowak D, von Mutius E, Weiland SK. Smoking and the incidence of asthma during adolescence: results of a large cohort study in Germany. Thorax. 2006 Jul;61(7):572-8.
108. Karadag B, Ege M, Bradley JE, Braun-Fahrlander C, Riedler J, Nowak D, von Mutius E. The role of parasitic infections in atopic diseases in rural schoolchildren.Allergy. 2006 Aug;61(8):996-1001.
109. Stern DA, Riedler J, Nowak D, Braun-Fahrlander C, Swoboda I, Balic N, Chen KW, Vrtala S, Gronlund H, van Hage M, Valenta R, Spitzauer S, Von Mutius E, Vercelli D. Exposure to a farming environment has allergen-specific protective effects on TH2-dependent isotype switching in response to common inhalants. J Allergy Clin Immunol. 2007 Feb;119(2):351-8.
110. Douwes J, Travier N, Huang K, Cheng S, Mckenzie J, Le gros G, von Mutius E, Pearce N. Lifelong farm exposure may strongly reduce the risk of asthma in adults. Allergy. 2007 Oct;62(10):1158-65.
111. Buchele G, Rzehak P, Weinmayr G, Keil U, Leupold W, von Mutius E, Weiland SK. Assessing bronchial responsiveness to hypertonic saline using the stepwise protocol of Phase Two of the International Study of Asthma and Allergies in Childhood (ISAAC II). Pediatr Pulmonol. 2007;42:131-40.
112. Ege MJ, Frei R, Bieli C, Schram-Bijkerk D, Waser M, Benz MR, Weiss G, Nyberg F, van Hage M, Pershagen G, Brunekreef B, Riedler J, Lauener R, Braun-Fahrlander C, von Mutius E; PARSIFAL Study team. Not all farming environments protect against the development of asthma and wheeze in children. J Allergy Clin Immunol. 2007;119:1140-7.
113. E. Riu, H. Dressel, D. Windstetter, G. Weinmayr, S. Weiland, C. Vogelberg, W. Leupold, E. von Mutius, D. Nowak and K. Radon. First months of employment and new onset of rhinitis in adolescents. Eur Respir J 2007; 30: 549–555.
114. Radon K, Windstetter D, Poluda AL, Muellera B, von Mutius E, Koletzko S and the Chronische Autoimmunerkrankungen und Kontakt zu Tieren (Chronic Autoimmune Disease and Animal Contact) Study Group. Contact With Farm Animals in Early Life and Juvenile Inflammatory Bowel Disease: A Case-Control Study. Pediatrics 2007;120;354-361.
115. Williams H, Stewart A, von Mutius E, Cookson W, Anderson HR; International Study of Asthma and Allergies in Childhood Phase One and Three Study Groups.Is eczema really on the increase worldwide?J Allergy Clin Immunol. 2008 Apr;121(4):947-54.e15.
116. Schedel M, Pinto LA, Schaub B, Rosenstiel P, Cherkasov D, Cameron L, Klopp N, Illig T, Vogelberg C, Weiland SK, von Mutius E, Lohoff M, Kabesch M. IRF-1 Gene Variations Influence IgE Regulation and Atopy. Am J Respir Crit Care Med. 2008 Mar 15;177(6):613-21.
117. Pinto LA, Steudemann L, Depner M, Klopp N, Illig T, Weiland SK, von Mutius E, Kabesch M.STAT1 gene variations, IgE regulation and atopy.Allergy. 2007 Dec;62(12): 1456-61.
118. Karadag B, Ege MJ, Scheynius A, Waser M, Schram-Bijkerk D, van Hage M, Pershagen G, Brunekreef B, Riedler J, Braun-Fahrländer C, von Mutius E; PARSIFAL Study Team.Environmental determinants of atopic eczema phenotypes in relation to asthma and atopic sensitization. Allergy. 2007 Dec;62(12):1387-93.
119. Flohr C, Weiland SK, Weinmayr G, Björkstén B, Bråbäck L, Brunekreef B, Büchele G, Clausen M, Cookson WO, von Mutius E, Strachan DP, Williams HC; the ISAAC Phase Two Study Group.The role of atopic sensitization in flexural eczema: Findings from the International Study of Asthma and Allergies in Childhood Phase Two.J Allergy Clin Immunol. 2008 Jan;121(1):141-147.e4.
120. Bieli C, Eder W, Frei R, Braun-Fahrländer C, Klimecki W, Waser M, Riedler J, von Mutius E, Scheynius A, Pershagen G, Doekes G, Lauener R, Martinez FD; PARSIFAL study group. A polymorphism in CD14 modifies the effect of farm milk consumption on allergic diseases and CD14 gene expression. J Allergy Clin Immunol. 2007 Dec;120(6):1308-15.
121. Moffatt MF, Kabesch M, Liang L, Dixon AL, Strachan D, Heath S, Depner M, von Berg A, Bufe A, Rietschel E, Heinzmann A, Simma B, Frischer T, Willis-Owen SA, Wong KC, Illig T, Vogelberg C, Weiland SK, von Mutius E, Abecasis GR, Farrall M, Gut IG, Lathrop GM, Cookson WO.Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma. Nature. 2007 Jul 26;448(7152):470-3.
122. Vogelberg C, Hirsch T, Radon K, Dressel H, Windstetter D, Weinmayr G, Weiland SK, von Mutius E, Nowak D, Leupold W.Leisure time activity and new onset of wheezing during adolescence.Eur Respir J. 2007 Oct;30(4):672-6.
123. Weinmayr G, Weiland SK, Björkstén B, Brunekreef B, Büchele G, Cookson WO, Garcia-Marcos L, Gotua M, Gratziou C, van Hage M, von Mutius E, Riikjärv MA, Rzehak P, Stein RT, Strachan DP, Tsanakas J, Wickens K, Wong GW; ISAAC Phase Two Study Group. Atopic sensitization and the international variation of asthma symptom prevalence in children. Am J Respir Crit Care Med. 2007 Sep 15;176(6):565-74.
124. Korthals M, Ege MJ, Tebbe CC, von Mutius E, Bauer J. Application of PCR-SSCP for molecular epidemiological studies on the exposure of farm children to bacteria in environmental dust. J Microbiol Methods. 2008 Apr;73(1):49-56.
125. Orsmark-Pietras C, Melén E, Vendelin J, Bruce S, Laitinen A, Laitinen LA, Lauener R, Riedler J, von Mutius E, Doekes G, Wickmann M, van Hage M, Pershagen G, Scheynius A, Nyberg F, Kere J; the PARSIFAL Genetics Study Group. Biological and genetic interaction between Tenascin C and Neuropeptide S receptor 1 in allergic diseases. Hum Mol Genet. 2008 Jun 1;17(11):1673-82.
126. Korthals M, Ege M, Lick S, von Mutius E, Bauer J. Occurrence of Listeria spp. In mattress dust of farm children in Bavaria. Environ Res. 2008 Jul;107(3):299-304.
127. Weidinger S, O’Sullivan M, Illig T, Baurecht H, Depner M, Rodriguez E, Ruether A, Klopp N, Vogelberg C, Weiland SK, McLean WH, von Mutius E, Irvine AD, Kabesch M. Filaggrin mutations, atopic eczema, hay fever, and asthma in children. J Allergy Clin Immunol. 2008 May;121(5):1203-1209.e1.
128. Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, Gohlke H, Wagenpfeil S, Ollert M, Ring J, Behrendt H, Heinrich J, Novak N, Bieber T, Krämer U, Berdel D, von Berg A, Bauer CP, Herbarth O, Koletzko S, Prokisch H, Mehta D, Meitinger T, Depner M, von Mutius E, Liang L, Moffatt M, Cookson W, Kabesch M, Wichmann HE, Illig T. Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 2008 Aug;4(8):e1000166.
129. Beasley R, Clayton T, Crane J, von Mutius E, Lai CKW, Montefort S, Stewart A and the ISAAC Phase Three Study Group. Paracetamol use in infancy and later childhood and risk of asthma, rhinoconjunctivitis and eczema in 6 to 7 year old children: ISAAC Phase Three. Lancet, 2008 Sep 20;372(9643):1039-48.
130. Michels KB, Waser M, Ary E, Rosenlund H, von Mutius E, Riedler J, Schram D, Pershagen G, Braun-Fahrlaender & the PARSIFAL Study Group. Validation of a questionnaire to assess dietary habits among 5–13-year old school children of farmers and anthroposophic families. Journal of Nutritional &Environmental Medicine 2008; 17(3): 157–168.
131. Schaub B, Liu J, Schleich I, Höppler S, Sattler C, von Mutius E. Impairment of T helper and T regulatory cell responses at birth. Allergy. 2008 Nov;63(11):1438-47.
132. Grüber C, Warner J, Hill D, Bauchau V; EPAAC Study Group. Early atopic disease and early childhood immunization--is there a link? Allergy. 2008 Nov;63(11):1464-72.
133. Ege MJ, Herzum I, Büchele G, Krauss-Etschmann S, Lauener RP, Bitter S, Roponen M, Remes S, Vuitton DA, Riedler J, Brunekreef B, Dalphin JC, Braun-Fahrländer C, Pekkanen J, Renz H, von Mutius E; PASTURE Study Group. Specific IgE to allergens in cord blood is associated with maternal immunity to Toxoplasma gondii and rubella virus. Allergy. 2008 Nov;63(11):1505-11.
134. Bieli C, Frei R, Schickinger V, Steinle J, Bommer C, Loeliger S, Braun-Fahrländer C, von Mutius E, Pershagen G, Lauener R. Gene expression measurements in the context of epidemiological studies. Allergy. 2008 Dec;63(12):1633-6.
135. Suttner K, Ruoss I, Rosenstiel P, Depner M, Pinto LA, Schedel M, Adamski J, Illig T, Schreiber S, von Mutius E, Kabesch M. HLX1 gene variants influence the development of childhood asthma. J Allergy Clin Immunol. 2009 Jan;123(1):82-88.e6.
136. Bruce S, Nyberg F, Melén E, James A, Pulkkinen V, Orsmark-Pietras C, Bergström A, Dahlén B, Wickman M, von Mutius E, Doekes G, Lauener R, Riedler J, Eder W, van Hage M, Pershagen G, Scheynius A, Kere J. The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms. J Med Genet. 2009 Mar;46(3):159-67.
137. Rosenlund H, Bergström A, Alm JS, Swartz J, Scheynius A, van Hage M, Johansen K, Brunekreef B, von Mutius E, Ege MJ, Riedler J, Braun-Fahrländer C, Waser M, Pershagen G; PARSIFAL Study Group. Allergic disease and atopic sensitization in children in relation to measles vaccination and measles infection. Pediatrics. 2009 Mar;123(3):771-8.
138. Pinto LA, Depner M, Steudemann L, Klopp N, Illig T, von Mutius E, Kabesch M. IL15 gene variants are not associated with asthma and atopy. Allergy. 2009 Apr;64(4):643-6.
139. Kormann MS, Ferstl R, Depner M, Klopp N, Spiller S, Illig T, Vogelberg C, von Mutius E, Kirschning CJ, Kabesch M. Rare TLR2 mutations reduce TLR2 receptor function and can increase atopy risk. Allergy. 2009 Apr;64(4):636-42.
140. Schaub B, Liu J, Höppler S, Schleich I, Huehn J, Olek S, Wieczorek G, Illi S, von Mutius E. Maternal farm exposure modulates neonatal immune mechanisms through regulatory T cells. J Allergy Clin Immunol. 2009 Apr;123(4):774-82.e5.
141. Nagel G, Büchele G, Weinmayr G, Björkstén B, Chen YZ, Wang H, Nystad W, Saraclar Y, Bråbäck L, Batlles-Garrido J, Garcia-Hernandez G, Weiland SK; ISAAC Phase II Study Group. Effect of breastfeeding on asthma, lung function and bronchial hyperreactivity in ISAAC Phase II.Eur Respir J. 2009 May; 33(5):993-1002.
142. Ganguly K, Depner M, Fattman C, Bein K, Oury TD, Wesselkamper SC, Borchers MT, Schreiber M, Gao F, von Mutius E, Kabesch M, Leikauf GD, Schulz H. Superoxide dismutase 3, extracellular (SOD3) variants and lung function. Physiol Genomics. 2009 May 13;37(3):260-7.
143. Suttner K, Depner M, Klopp N, Illig T, Vogelberg C, Adamski J, von Mutius E, Kabesch M. Genetic variants in the GATA3 gene are not associated with asthma and atopic diseases in German children. J Allergy Clin Immunol. 2009 May;123(5):1179-81.
144. Suttner K, Rosenstiel P, Depner M, Schedel M, Pinto LA, Ruether A, Adamski J, Klopp N, Illig T, Vogelberg C, Schreiber S, von Mutius E, Kabesch M. TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. J Allergy Clin Immunol. 2009 May;123(5):1062-8, 1068.e1-8.
145. Sudre B, Vacheyrou M, Braun-Fahrländer C, Normand AC, Waser M, Reboux G, Ruffaldi P, von Mutius E, Piarroux R; PASTURE study group. High levels of grass pollen inside European dairy farms: a role for the allergy-protective effects of environment? Allergy. 2009 Jul;64(7):1068-73.
146. Bousquet J, Burney PG, Zuberbier T, Cauwenberge PV, Akdis CA, Bindslev-Jensen C, Bonini S, Fokkens WJ, Kauffmann F, Kowalski ML, Lodrup-Carlsen K, Mullol J, Nizankowska-Mogilnicka E, Papadopoulos N, Toskala E, Wickman M, Anto J, Auvergne N, Bachert C, Bousquet PJ, Brunekreef B, Canonica GW, Carlsen KH, Gjomarkaj M, Haahtela T, Howarth P, Lenzen G, Lotvall J, Radon K, Ring J, Salapatas M, Schünemann HJ, Szczecklik A, Todo-Bom A, Valovirta E, von Mutius E, Zock JP. GA2LEN (Global Allergy and Asthma European Network) addresses the allergy and asthma 'epidemic'. Allergy. 2009 Jul;64(7):969-77.
147. Ekelund E, Bradley M, Weidinger S, Jovanovic DL, Johanson C, Lindgren CM, Todorova A, Jakob T, Illig T, von Mutius E, Braun-Fahrländer C, Doekes G, Riedler J, Scheynius A, Pershagen G, Kockum I, Kere J. Lack of Association between Neuropeptide S Receptor 1 Gene (NPSR1) and Eczema in Five European Populations. Acta Derm Venereol 2009; 89: 115–121.
148. Karvonen AM, Hyvärinen A, Roponen M, Hoffmann M, Korppi M, Remes S, von Mutius E, Nevalainen A, Pekkanen J. Confirmed moisture damage at home, respiratory symptoms and atopy in early life: a birth-cohort study. Pediatrics. 2009 Aug;124(2):e329-38.
149. Ellwood P, Williams H, Aït-Khaled N, Björkstén B, Robertson C and the ISAAC Phase III Study Group. Translation of questions: the International Study of Asthma and Allergies in Childhood (ISAAC) experience. Int J Tuberc Lung Dis 2009; 13(9):1174–1182.
150. Cameron L, Depner M, Kormann M, Klopp N, Illig T, von Mutius E, Kabesch M. Genetic variation in CRTh2 influences development of allergic phenotypes. Allergy. 2009 Oct;64(10):1478-85.
151. Flohr C, Weinmayr G, Weiland SK, Addo-Yobo E, Annesi-Maesano I, Björkstén B, Bråbäck L, Büchele G, Chico M, Cooper P, Clausen M, El Sharif N, Martinez Gimeno A, Mathur RS, von Mutius E, Morales Suarez-Varela M, Pearce N, Svabe V, Wong GW, Yu M, Zhong NS, Williams HC; ISAAC Phase Two Study Group. How well do questionnaires perform compared with physical examination in detecting flexural eczema? Findings from the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Two. Br J Dermatol. 2009 Oct;161(4):846-53.
152. Heinzerling LM, Burbach GJ, Edenharter G, Bachert C, Bindslev-Jensen C, Bonini S, Bousquet J, Bousquet-Rouanet L, Bousquet PJ, Bresciani M, Bruno A, Burney P, Canonica GW, Darsow U, Demoly P, Durham S, Fokkens WJ, Giavi S, Gjomarkaj M, Gramiccioni C, Haahtela T, Kowalski ML, Magyar P, Muraközi G, Orosz M, Papadopoulos NG, Röhnelt C, Stingl G, Todo-Bom A, von Mutius E, Wiesner A, Wöhrl S, Zuberbier T. GA(2)LEN skin test study I: GA(2)LEN harmonization of skin prick testing: novel sensitization patterns for inhalant allergens in Europe. Allergy. 2009 Oct;64(10):1498-506.
153. Burbach GJ, Heinzerling LM, Edenharter G, Bachert C, Bindslev-Jensen C, Bonini S, Bousquet J, Bousquet-Rouanet L, Bousquet PJ, Bresciani M, Bruno A, Canonica GW, Darsow U, Demoly P, Durham S, Fokkens WJ, Giavi S, Gjomarkaj M, Gramiccioni C, Haahtela T, Kowalski ML, Magyar P, Muraközi G, Orosz M, Papadopoulos NG, Röhnelt C, Stingl G, Todo-Bom A, von Mutius E, Wiesner A, Wöhrl S, Zuberbier T. GA(2)LEN skin test study II: clinical relevance of inhalant allergen sensitizations in Europe. Allergy. 2009 Oct;64(10):1507-15.
154. Bousquet PJ, Burbach G, Heinzerling LM, Edenharter G, Bachert C, Bindslev-Jensen C, Bonini S, Bousquet-Rouanet L, Demoly P, Bresciani M, Bruno A, Gjomarkaj M, Canonica GW, Darsow U, Durham S, Fokkens WJ, Giavi S, Gramiccioni C, Papadopoulos NG, Haahtela T, Kowalski ML, Magyar P, Muraközi G, Orosz M, Röhnelt C, Stingl G, Todo-Bom A, von Mutius E, Wiesner A, Wöhrl S, Bousquet J, Zuberbier T. GA2LEN skin test study III: minimum battery of test inhalent allergens needed in epidemiological studies in patients. Allergy. 2009 Nov;64(11):1656-62.
155. Foliaki S, Pearce N, Björkstén B, Mallol J, Montefort S, von Mutius E; International Study of Asthma and Allergies in Childhood Phase III Study Group. Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies in Childhood Phase III. J Allergy Clin Immunol. 2009 Nov;124(5):982-9.
156. Pfefferle PI, Büchele G, Blümer N, Roponen M, Ege MJ, Krauss-Etschmann S, Genuneit J, Hyvärinen A, Hirvonen MR, Lauener R, Pekkanen J, Riedler J, Dalphin JC, Brunekeef B, Braun-Fahrländer C, von Mutius E, Renz H; on behalf of the PASTURE Study Group. Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: The PASTURE Study. J Allergy Clin Immunol. 2010 Jan;125(1):108-115.e3.
157. Conrad ML, Ferstl R, Teich R, Brand S, Blümer N, Yildirim AO, Patrascan CC, Hanuszkiewicz A, Akira S, Wagner H, Holst O, von Mutius E, Pfefferle PI, Kirschning CJ, Garn H, Renz H. Maternal TLR signaling is required for prenatal asthma protection by the nonpathogenic microbe Acinetobacter lwoffii F78. J Exp Med. 2009 Dec 21;206(13):2869-77.
158. Weinmayr G, Genuneit J, Nagel G, Björkstén B, van Hage M, Priftanji A, Cooper P, Rijkjärv MA, von Mutius E, Tsanakas J, Forastiere F, Doekes G, Garrido JB, Suarez-Varela MM, Bråbäck L, Strachan DP; the ISAAC Phase Two Study Group*. International variations in associations of allergic markers and diseases in children: ISAAC Phase Two. Allergy. 2009 Dec 21. [Epub ahead of print]
159. Rochat MK, Ege MJ, Plabst D, Steinle J, Bitter S, Braun-Fahrländer C, Dalphin JC, Riedler J, Roponen M, Hirvonen MR, Büchele G, Renz H, Lauener R, Krauss-Etschmann S, von Mutius E; the PASTURE Study group. Maternal vitamin D intake during pregnancy increases gene expression of ILT3 and ILT4 in cord blood. Clin Exp Allergy. 2009 Dec 16. [Epub ahead of print]
160. Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JM, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H. Variants of DENND1B associated with asthma in children. N Engl J Med. 2010 Jan 7;362(1):36-44.
161. Genuneit J, Cantelmo JL, Weinmayr G, Wong GW, Cooper PJ, Riikjärv MA, Gotua M, Kabesch M, von Mutius E, Forastiere F, Crane J, Nystad W, El-Sharif N, Batlles-Garrido J, García-Marcos L, García-Hernández G, Morales-Suarez-Varela M, Nilsson L, Bråbäck L, Saraçlar Y, Weiland SK, Cookson WO, Strachan D, Moffatt MF; ISAAC Phase 2 Study Group. A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2. Clin Exp Allergy. 2009 Dec;39(12):1875-88.

Review articles / editorials:
1. von Mutius E. Luftschadstoffe und Atemwegserkrankungen im Kindesalter. Öff.Gesundh.-Wes 1988;50:325-8.
2. Oberbauer B, Nicolai T, von Mutius E. Asthma bronchiale im Kindesalter. Teil I: klinische Erscheinungsformen, Diagnose und Grundregeln der Therapie. Fortschr Med 1993;111:457-60.
3. Oberbauer B, Nicolai T, von Mutius E. Asthma bronchiale im Kindesalter. Teil II: Stufenplan der medikamentösen Therapie. Fortschr Med 1993;111:473-5.
4. Nicolai T, von Mutius E, Reitmeir P, Wjst M. Kaltluft-Hyperventilations-provokation. Pneumologie 1993;47:67-8.
5. von Mutius E, Urbanek R. Untersuchung der bronchialen Hyperreagibilität und Epidemiologie des Asthma bronchiale im Kindesalter. Pneumologie 1993;47:73-5.
6. von Mutius E. Passivrauchen - Auswirkungen auf den kindlichen Respirationstrakt. In: Kinderarzt und Umwelt. Jahrbuch 1993/94, S. 90-97. Hrsgb. K.E.v.Mühlendahl.
7. von Mutius E, Pforte A. Asthma bronchiale. Internist, 1994;35:232-8.
8. von Mutius E. Atopy and bronchial hyperresponsiveness in children. ACI News 1995;7: 179-82.
9. von Mutius E. Progression of allergy and asthma through childhood to adolescence. Thorax 1996;51:1-3.
10. von Mutius E. Epidemiology of asthma: ISAAC—International Study of Asthma and Allergies in Childhood. Pediatr Allergy Immunol 1996;7(9 Suppl):54-6.
11. von Mutius E. Umweltfaktoren bei der Entstehung von Asthma und allergischen Erkrankungen in Ost- und Westdeutschland. Rundgespräche der Kommission für Ökologie, 1996;11:131-41.
12. von Mutius E. Genetik oder Umwelt ? (Editorial). Münchn Med Wschr 1996;138:115.
13. von Mutius E. Progression of allergy and asthma through childhood to adolescence. Thorax. 1996; 51 Suppl 1:S3-6.
14. von Mutius E. Atopie und Asthma bronchiale im Kindesalter. Eine Einführung. Allergologie 1996;19:302-9.
15. Nicolai T, von Mutius E. Respiratory hypersensitivity and environmental factors: East and West Germany. Toxicology letters 1996;86:105-13.
16. von Mutius E. Infection and Pollution. Pediatr Pulmonol Suppl. 1997;16:203-4.
17. von Mutius E. Epidemiology of Asthma: ISAAC - International Study of Asthma and Allergies in Childhood. Pediatr Allergy Immunol 1996;7 (Suppl):54-6.
18. Nicolai T, von Mutius E. Pollution and the development of allergy: the East and West Germany story. Arch Toxicol Suppl. 1997;19:201-6.
19. von Mutius E. Towards prevention. Lancet 1997;350 (suppl II):14-7.
20. von Mutius E. Epidemiologie des Asthma bronchiale im Kindesalter. Pneumologie 1997;51:949-61.
21. von Mutius E. Indoor and Outdoor Air Pollution and Childhood Asthma. Ped Pulmonology 1997;16(Suppl):86-7.
22. von Mutius E. Infection and Pollution. Ped Pulmonology 1997;16(Suppl):203-4.
23. von Mutius E, Mrach M, Oberneder B. Wenn Kinder mit Heuschnupfen in die Praxis kommen. Behandlungsmöglichkeiten, die man bei allergischer Rhinokonjunktivitis nutzen kann. Forschung und Praxis 1997;234:6-8.
24. Wahn U, Bergmann R, Lau S, von Mutius E. Environmental factors in the development of atopy and asthma in children. Asthma and Allergic Diseases: Physiology, Immunopharmacology, and Treatment 1998: 47- 56.
25. von Mutius E. Determinants of childhood asthma and atopy in West and East Germany. Eur Respir Review 1998;8:145-7.
26. von Mutius E. The natural history of asthma from pre-birth to adulthood. Eur Respir Review 1998;8:308-11.
27. von Mutius E. Allergy and the environment. Allergy. 1999;54 Suppl 56:16-7.
28. von Mutius E, Weiland SK, Keil U für das ISAAC Steering Committee. Die Internationale Studie zu Asthma und Allergien im Kindesalter (ISAAC): Forschungsstrategie und Methoden der Phase II: Allergologie 1999;22:283-8.
29. Weiland SK, von Mutius E, Keil U für das ISAAC Steering Committee. Die International Study of Asthma and Allergies in Childhood (ISAAC): Forschungsstrategie, Methoden und Ausblick: Allergologie 1999;22:275-82.
30. von Mutius E. Asthma und Infekte: Risiko oder Schutz? Schweiz Med Wochenschr 1998;128:1833-9.
31. von Mutius E. The influence of birth order on the expression of atopy in families: a gene-environment interaction? (Editorial). Clin Exp Allergy 1998;28:1454-6.
32. von Mutius E. The rising trends in asthma and allergic disease. Clin Exp Allergy. 1998 Nov;28 Suppl 5:45-9; discussion 50-1.
33. von Mutius E. The rising trends in asthma and allergic disease. Clin Exp Allergy 1998;28:45-9.
34. von Mutius E. Sensibilisierung auf Küchenschaben. Ein neues Allergieproblem in Industriestaaten ? MMW-Fortschr Med 1999;22:41.
35. von Mutius E. Allergy and the environment. Allergy 1999;56(Suppl):18-20.
36. von Mutius E. Role of immunisations and infections for the development of atopy. Rev Fr Allergol 1999;39:649-52.
37. Sterk PJ, Buist SA, Woolcock AJ, Marks GB, Platts-Mills TAE, von Mutius E, Bousquet J, Frew AJ, Pauwels RA, Ait-Khaled N, Hill SL, Partridge MR. The message from the World Asthma Meeting. Eur Respir J 1999;14;1435-53.
38. von Mutius E. The environmental predictors of allergic diseases. J Allergy Clin Immunol 2000;105:9-19.
39. Kabesch M, von Mutius E. Adverse health effects of environmental tobacco smoke exposure in childhood. ACI International 2000;12;146-52.
40. von Mutius E. Statistical / design methods. Am J Respir Crit Care Med 2000;162:S34-5.
41. von Mutius E. Presentation of new GINA guidelines for pediatrics. Clin Exp Allergy 2000;30(suppl):6-10.
42. von Mutius E. The burden of childhood asthma. Arch Dis Child 2000;82:0-3.
43. von Mutius E. Ein traditioneller bäuerlicher Lebensstil - Schutzfaktor vor Allergien? (Editorial). (A traditional farming life style - does it confer protection against allergies?). Dtsch Med Wschr 2000;125(31-32): 923
44. von Mutius E. Augmentation de prévalence de l’asthme et des allergies. AER 2000;3:123-8.
45. von Mutius E. Paediatric origins of adult lung disease. Thorax 2001;56:153-7.
46. von Mutius E. Rolle der Allergenexposition für die Entstehung allergischer Erkrankungen. Allergologie 2000.
47. von Mutius E. The burden of childhood asthma. Arch Dis Child. 2000;82 Suppl 2:II2-5.
48. von Mutius E. Presentation of new GINA guidelines for paediatrics. The Global Initative on Asthma. Clin Exp Allergy 2000;30 Suppl 1:6-10.
49. von Mutius E. A traditional farming environment – a prophylactic factor against allergies. Dtsch Med Wochenschr. 2000;125:923.
50. Wahn U, von Mutius E. Childhood risk factors for atopy and the importance of early intervention. J Allergy Clin Immunol 2001;107:567-74.
51. von Mutius E. Peut-on modifier l’histoire naturelle de l’asthme ? Rev Fr Allergol Immunol Clin 2000;40:689-94.
52. von Mutius E. The environmental predictors of allergic disease. J Allergy Clin Immunol. 2000;105:9-19.
53. von Mutius E. Epidemiologie des Asthma bronchiale. Monatschr Kinderheilk 2001;149:86-93.
54. Hirsch T, Weiland SK, von Mutius E. Pollenflug und allergische Sensibilisierung gegen Frühblüher bei Kindern in München und Dresden. Pneumologie 2001;55:223.
55. von Mutius E. Is asthma really linked to atopy? (Editorial). Clin Exp Allergy 2001;31:1651-2.
56. von Mutius E. The increase in asthma can be ascribed to cleanliness. (Pro/Con editorial) Am J Respir Crit Care 2001;164:1-4.
57. von Mutius E. Paediatric origins of adult lung disease. Thorax. 2001;56:153-7. Review.
58. Oberle D, von Kries R, von Mutius E. Asthma and breast feeding. Thorax 2001;56:896.
59. Hirsch T, Weiland SK, von Mutius E. Pollen count and allergic sensitization against early pollinators in children in Munich and Dresden. Pneumologie. 2001;55:223.
60. von Mutius E. Childhood experiences take away your breath as a young adult (editorial). Am J Respir Crit Care Med. 2002; 165:1467-8.
61. von Mutius E. Environmental factors influencing the development and progression of pediatric asthma. J Allergy Clin Immunol. 2002; 109(6 Suppl):S525-32.
62. Kabesch M, von Mutius E. Prevention of asthma in childhood. Dtsch Med Wochenschr. 2002; 127:1506-8.
63. Wahn U, von Mutius E. Childhood risk factors for atopy and the importance of early intervention. J Allergy Clin Immunol. 2001;107:567-74.
64. Lau S, Nickel R, Niggemann B, Gruber C, Sommerfeld C, Illi S, Kulig M, Forster J, Wahn U, Groeger M, Zepp F, Kamin W, Bieber I, Tacke U, Wahn V, Bauer CP, Bergmann R, von Mutius E; MAS Group. The development of childhood asthma: lessons from the German Multicentre Allergy Study (MAS). Pediatr Respir Rev. 2002;3:265-72.
65. Illi S, von Mutius E. House-dust mite allergen exposure and the development of asthma in children. Ann Allergy Asthma Immunol. 2003;90:6-7.
66. Nickel R, Lu S, Niggemann B, Gruber C, von Mutius E, Illi S, Kulig M, Wahn U, MAS-Group. Messages from the German Multicentre Allergy Study. Pediatr Allergy Immunol. 2002; 13 Suppl 15:7-10.
67. von Mutius E. A conundrum of modern times that’s still unresolved. Eur Respir J. 2003;22:719-20.
68. Nowak D, von Mutius E. Bronchial asthma in children and adults: risk factors, diagnosis and standard treatment. Dtsch Med Wochenschr. 2004;129:509-16.
69. Eder W, von Mutius E. Hygiene hypothesis and endotoxin: what is the evidence? Curr Opin Allergy Clin Immunol. 2004;4:113-17.
70. von Mutius E. Influences in allergy: epidemiology and the environment. J Allergy Clin Immunol. 2004;113:373-9.
71. Nowak D, Suppli Ulrik C, von Mutius E. Asthma and atopy: has peak prevalence been reached? Eur Respir J. 2004;23:359-60.
72. Schaub B, von Mutius E. The marketing of asthma and allergies. Lancet 2004;364:1389-90.
73. Radon K, Dressel H, Hümmer S, Riu E, Nowak D, Weinmayr G, Genuneit J, Weiland St, Vogelberg Ch, Leupold W, Windstetter D, von Mutius E, Kupfer J. Berufliche Allergierisiken – Die SOLAR-Kohortenstudie. Schriftenreihe der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin. Dortmund/Berlin/Dresden 2005.
74. von Mutius E. Allergien lassen sich nicht über einen Kamm scheren. MMW Fortschr.Med 2006;148:26-8.
75. Kabesch M, Kauffmann F, von Mutius E. New ways in respiratory genetics (editorial). Eur Resp J 2006;28: 1079-80.
76. von Mutius E. Allergies, infections and the hygiene hypothesis – The epidemiological evidence. Immunobiology 2007; 212: 433-439.
77. von Mutius E, Le Souef P. Early gene-environment interactions: can they inform primary preventive strategies for asthma? Semin Respir Crit Care Med 2007;28:255-63.
78. von Mutius E. Allergies, infections and the hygiene hypothesis – the epidemiological evidence. Immunobiology 2007;212:433-39.
79. von Mutius E. Of attraction and rejection – asthma and the microbial world. (Editorial) NEJM 2007; Oct 11;357(15):1545-7.
80. von Mutius E, Radon K. Living on a Farm: Impact on Asthma Induction and Clinical Course. Immunol Allergy Clin N Am 2008;28:631–647.
81. von Mutius E. Genes and the environment: Two readings of their interaction. J Allergy Clin Immunol. 2008 Jul;122(1):99-100.
82. Sly PD, Boner AL, Björksten B, Bush A, Custovic A, Eigenmann PA, Gern JE, Gerritsen J, Hamelmann E, Helms PJ, Lemanske RF, Martinez F, Pedersen S, Renz H, Sampson H, von Mutius E, Wahn U, Holt PG. Early identification of atopy in the prediction of persistent asthma in children. Lancet 2008;372:1100-1106.
83. von Mutius E. Rhinitis as predictor of adult-onset asthma. (Editorial). Lancet 2008;372:1012-1013.
84. von Mutius E. Allergien und Asthma. Internist. 2008 Nov;49(11):1295-6, 1298, 1300-1.
85. von Mutius E. Gene-environment interactions in asthma. J Allergy Clin Immunol. 2009 Jan;123(1):3-11.
86.  Burbach GJ, Heinzerling LM, Röhnelt C, Bergmann KC, Behrendt H, Zuberbier T; GA(2)LEN study. Ragweed sensitization in Europe - GA(2)LEN study suggests increasing prevalence. Allergy. 2009 Apr;64(4):664-5.
87. Frey, U and von Mutius E. The Challenge of Managing Wheezing in Infants. (Editorial) New Engl J Med 2009;360:2130-2133 .

Book chapters:
1. von Mutius E. Asthma and Atopy in West and East Germany. In: New Trends in Allergy IV. Hrsgb: Ring J. 1996;37-42.
2. von Mutius E. Epidemiologie. Risikofaktoren aus Umwelt und Lebensweise. In: Allergologie. Hrsgb: Heppt W, Renz H, Röcken M. Springer 1997.
3. von Mutius E. Genetische Disposition allergischer Erkrankungen. In: Die Ursachen der Allergie: Gene-Umwelt-Nahrungsmittel. Hrsgb: Mösges R, Schlöndorff G, Biermann Verlag, Zülpich, 1997, in Press.
4. von Mutius E. The application of modern epidemiological methods to paediatric respiratory disorders. In: European Respiratory Monograph, 1997 Monograph 5, Volume 2, pp. 236-276.
5. von Mutius E. Epidemiologie allergischer Erkrankungen im Kindesalter. Pädiatrische Allergologie und Immunologie. Hrsgb: Wahn U, Seger R, Wahn V. Gustav Fischer Verlag, 1999, S. 159-72.
6. von Mutius E, Morgan W. Acute, chronic and wheezy bronchitis. In: Pediatric Pulmonology. Hrsgb: L.Taussig, P.Phelan. 1998, in press.
7. von Mutius E, Martinez FD. Epidemiology of childhood asthma. In: Pediatric Asthma. Hrsgb: Murphy S, Kelly HW. Lung Biology in Health and Disease. Marcel Dekker 1999;126:1-40.
8. von Mutius E. Air pollution and asthma. In: Immunotherapy in Asthma. Hrsgb: Bousquet J, Yssel H. Series Lung Biology in Health and Disease. 1999;136:497-534.
9. von Mutius E. Umwelt und respiratorische Morbidität. In: Pädiatrische Pneumologie. Hrsgb: Rieger C, von der Hardt H, Wahn U, Zach M, Sennhauser F. Springer Verlag, 1999:505-28.
10. von Mutius E. Epidemiologie. In: Asthma bronchiale im Kindesalter. Hrsgb Reinhardt D. Springer Verlag, 1999;S. 8-16, S. 22-34.
11. von Mutius E. Atemwegserkrankungen bei Kindern. In: Pneumologische Umweltmedizin. Hrsgb. Schultz K, Petro W. 1999: S. 109-18.
12. Nowak D, von Mutius E. Epidemiologische und sozialmedizinische Aspekte des Asthma bronchiale im Kindes- und Erwachsenenalter. In: Asthma bronchiale. Hrsgb: Petermann F, Warschburger P. 1999; S. 35-64.
13. von Mutius E. Environmental factors and rising time trends in prevalence and severity. In: Difficult asthma. Hrsgb: Holgate ST, Boushey HA, Fabbri LM. Martin Dunitz 1999; pp. 53-76.
14. Kabesch M, von Mutius E. Risk factors for wheezing with upper respiratory tract infections in children. In: Series Lung Biology in Health and Disease. Asthma and Respiratory Infections. Hrsgb: Skoner DP. Marcel Dekker New York, 2000; pp. 63-88.
15. Nowak D, von Mutius E. Epidemiologie der obstruktiven Atemwegserkrankungen, speziell des Asthma bronchiale. In: pneumologische Prävention und Rehabilitation. Hrsgb: Petro W. Springer Berlin 2000;93-108.
16. von Mutius E. Schadstoffwirkungen und respiratorische Morbidität. Pädiatrie. Grundlagen und Praxis. Hrsgb: Lentze MJ, Schaub J, Schulte FJ, Spranger J. Springer Berlin 2000; 1009-12.
17. von Mutius E. Why is asthma more common in the West ?. In: Asthma. Critical Debates. Hrsgb: Holgate S, Johnston S. Blackwell Science London, Edinburgh,Victoria, Paris 2002, pp 18-34.
18. von Mutius E. Worldwide Asthma Epidemic. In: Immunology and Allergy Clinics of North America. Ed: Finn PW. W.B. Saunders Company, 2002, Volume 22, Number 4, pp701-12.
19. von Mutius E. Epidemiology of Allergic Diseases. In: Pediatric Allergy. Principles and Practice. Hrsgb: Leung DYM, Sampson HA, Geha RS, Szefler SJ. Mosby, Inc. St. Louis, 2003, pp 1-9.
20. Kabesch M, von Mutius E. Monde moderne et allergies. In: Traité d’Allergologie. Hrsgb: Vervloet D, Magnan A. Médecine-Sciences Flammarion, Paris 2003, pp 371-80.
21. von Mutius E, Braun-Fahrländer Ch. Preventing asthma: the role of farm animals, pets, endotoxins and probiotics. In: Paediatric Asthma and Allergy. Hrsgb: Dinwiddie R, Brand PLP, Pohunek P. Quay Books, MA Healthcare Limited. 2004, pp 1-6.
22. von Mutius E. Epidemiologie allergischer Erkrankungen. In: Allergologie-Handbuch. Grundlagen und klinische Praxis.Hrsgb: Saloga J, Klimek L, Buhl R, Mann W, Knop J. Schattauer Verlag Stuttgart New York 2005, 184-194.
23. Rochat M, von Mutius E. Birth Cohort Studies for the Prevention of Allergy: New Perspectives—Where Do We Go from Now? In: Allergy Frontiers: Therapy and Prevention. Ed: Pawankar R, Holgate ST, Rosenwasser LJ. Springer 2009, Vol. 5, pp 397-415.